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Home Blood Cancer

Ca 125 Ovarian Cancer – What Is It?

Rebecca G. Miller by Rebecca G. Miller
September 15, 2025
in Blood Cancer
0

CA-125 Ovarian Cancer is a cancer marker originally designed to diagnose ovarian cancer. It’s also used for screening for other cancers as well as pregnancy. This marker is measured in units known as micrograms per liter.

A novel approach to treating ovarian cancer using a combination of a nanoparticle-based drug and radiotherapy in mice has been reported in the latest issue of Cell Reports. Hopefully, this may translate into better survival rates for women with ovarian cancer.

Cancer

Summary show
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CA-125 Ovarian Cancer
How to Detect Ovarian Cancer
How to Diagnose It?
What Are the Symptoms?
How to Treat It?
Frequently Asked Questions (FAQs)
Myths About Cancer
Conclusion

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CA-125 is highly specific for malignant ovarian tumors and has been used to diagnose various gynecological cancers, including ovarian cancer. This marker has a sensitivity of 60 to 80% and a specificity of 100%.

The CA 125 antigen is a tumor-associated carbohydrate antigen expressed in several types of cancer, including the ovary and breast, and in some benign conditions such as endometriosis.

CA-125 is a blood test used to check for ovarian cancer. Although it is not 100% accurate, it has been used to detect ovarian cancer in some cases. In this Ca 125 Ovarian Cancer Test review, I’ll discuss the pros and cons of the test to help you decide whether or not to do it.

If you’re looking for a test to help determine whether you have ovarian cancer, you’ll need a blood test called a CA-125. This blood test is used to detect cancerous cells that are often found in ovarian cancer.

The ovarian cancer test is a blood test that looks at the level of CA-125.

The level of CA-125 can be measured in several different ways.

CA-125 Ovarian Cancer

According to the American Cancer Society, 1 in 80 women will develop ovarian cancer in their lifetime, and approximately 14,000 new cases will be diagnosed in 2017 alone.

We all know the feeling of spotting a lump in our breasts or abdomen. While we may not always know what it is, we can all recognize the fear of being diagnosed with a serious disease.

However, some signs of ovarian cancer are not so obvious. Many ovarian cancers are detected only when they are already too advanced to be treated. Fortunately, there are several ways to detect ovarian cancer early, and you can learn more about them here.

If you’ve had an ovarian cyst, you know how painful it can be. But did you know that an ovarian cyst could be a symptom of an early ovarian cancer stage?

Early detection is the key to saving lives, especially regarding ovarian cancer.

The good news is that ovarian cancer has one of the lowest mortality rates for any cancer. The bad news is that only around 20% of women with ovarian cancer are diagnosed in the early stages, and most are already in advanced stages by the time they are diagnosed.

That’s why it’s important to know what symptoms to watch for and what tests to get before developing a large, painful cyst.

How to Detect Ovarian Cancer

CA-125 is a protein found on the surface of ovarian cancer cells. It is usually present at very high levels in patients with advanced ovarian cancer. Unfortunately, it is also high in patients with other conditions like endometriosis and pelvic inflammatory disease.

We use CA-125 as a screening test for ovarian cancer, which is elevated in patients with the disease. However, it is also present in patients with other conditions, which makes it a less-than-perfect test.

The main goal of this article is to review the current state of the art of Ca 125 ovarian cancer detection.

 

I am choosing Ca 125, which doctors have used for over 60 years, and aretill very useful in diagnosis. Ca 125 is a specific blood test only positive in patients with high protein CA 125.

Ca 125 is typically elevated in people with cancer but can also be elevated due to other noncancerous conditions, including infection, fibroids, endometriosis, etc.

Although the test is not 100% accurate, it does have a pretty good sensitivity.

How to Diagnose It?

The CA-125 antigen is a tumor-associated marker (TAM) found in many ovarian cancer types. This protein is also known as the MUC-16 antigen (Mucin 16). Ca 125 is produced by the majority of epithelial cancers originating from the surface of the ovary or fallopian tubes. The most common type of ovarian cancer is serous adenocarcinoma.

Ca 125 levels may be elevated in many benign conditions, including pregnancy, menstruation, ectopic pregnancy, and endometriosis. There is also a small percentage of women with malignant tumors of the ovaries who have normal CA-125 levels.

Ovarian cancer is one of the most common cancers among women. Early detection can mean the difference between successful treatment and death. However, it can be challenging to detect ovarian cancer early.

An important step towards early detection is knowing how to test for the disease. The CA-125 blood test can be used to detect ovarian cancer.

If you have questions about the CA-125 blood test, call your doctor or visit your local health department.

What Are the Symptoms?

OVCA is the fourth most common gynecological malignancy, accounting for 4% of all cancers in women. Ovarian cancer develops from the cells lining the ovaries (which produce female sex hormones), with symptoms usually appearing around the time cancer has spread to other body parts.

Most women have no symptoms when their cancer is first diagnosed, making early detection difficult. If you are experiencing symptoms, they may include:

• bloating

• abdominal swelling

• pain

• changes in bowel habits

• weight loss

• pain on one side of the belly

• backache

• nausea

• fatigue

A pelvic examination and transvaginal pelvic ultrasound are the initial exams to detect abnormalities.

How to Treat It?

CA-125 is a blood test used to screen for certain cancers. While this test may not be as accurate for other types of cancer, it is useful in determining if a woman has ovarian cancer.

Ca 125 levels will rise in the presence of cancer in the ovaries. They will also grow in benign conditions, such as cysts and fibroids.

CA-125 is often called an “ovarian cancer antigen.” It was first isolated in 1975 by Dr. George N. Hatsukami of the University of Utah School of Medicine.

 

Ovarian cancer has been linked to various environmental factors, including birth control pills. Women who have had multiple abortions are more likely to develop ovarian cancer. Smoking has also been associated with an increased risk.

The good news is that if the test shows you have ovarian cancer, it can be detected early. This means the treatment options are more effective, and your chances of recovery are higher.

Frequently Asked Questions (FAQs)

Q: Are there any symptoms of ovarian cancer?

A: Ovarian cancer can cause pain in the lower abdomen and back, weight gain, persistent or abnormal vaginal bleeding, and urinary frequency.

Q: Can ovarian cancer be cured?

A: Ovarian cancer is often treated with surgery, radiation therapy, and chemotherapy. However, the outcome depends on many factors, such as how early the disease is found and how far it has progressed. Some types of cancers are not curable, such as prostate cancer.

Q: Why is ovarian cancer more common than other forms of cancer?

A: Ovarian cancer is often discovered at an early stage. Other types of cancer may cause pain and are easier to detect than ovarian cancer.

Q: Is there anything that women can do to reduce their risk of ovarian cancer?

A: Women should learn about the symptoms of ovarian cancer and keep up with screening tests.

Q: Why did you decide to get tested for cancer?

A: I was just diagnosed with cancer and had all these questions. I wanted to know more about it, so I looked into it and discovered it is one of the most common types of ovarian cancer. It is estimated that over 20,000 women in the United States are diagnosed with this type of cancer each year.

Q: What are the symptoms of this type of cancer?

A: Most women do not know they have cancer until the tumor reaches a certain size, which can cause different symptoms. Symptoms include abdominal swelling, frequent urination or blood in the urine, vaginal bleeding, and pain during intercourse.

Q: What is the most common symptom of Ovarian cancer?

A: When the ovaries grow tumors, they often bleed (bleeding may or may not be a symptom). Other symptoms are unusual vaginal bleeding or pain during or after sex. If it is not discovered early enough, Ovarian cancer can spread to other body parts, including the lymph nodes and other organs.

Q: What are the different types of Ovarian cancer?

A: There are two main types of Ovarian cancer: the more common one (75% to 85%) is called epithelial Ovarian Cancer, and the second one (15% to 25%) is called germ cell Ovarian Cancer.

Myths About Cancer

1. OVCs are not treatable.

2. Women with CA-125 ovarian Cancer always have very advanced diseases.

3. The disease progresses very quickly, and no treatment is available.

Conclusion

The Ca 125 test is one of the most useful tests for ovarian cancer. It’s considered to be one of the first reliable screening tools.

However, the test is not without its limitations. If used alone, it cannot detect the early stages of cancer. It also isn’t very accurate when it comes to detecting benign tumors.

It can be used to monitor cancer treatment, but it is not useful in diagnosing ovarian cancer.

If you’d like to read a more in-depth review of this topic, check out my article here.

CA-125 is an antibody test that detects a specific protein ovarian cancer cells produce. This protein is called CA-125. It’s used to detect ovarian cancer.

The test looks for levels of this protein in your blood. High levels of this protein may indicate cancer.

Ca 125 test is part of routine blood tests done to check the health of a woman’s ovaries.

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